Vitamin D - 1033 Words

Vitamin D is an important micronutrient that is involved in the metabolism of calcium and phosphorous, and helps establish strong bone health (1). Recent studies have shown promising results of supplementing vitamin D to pregnant women with gestational diabetes mellitus (GDM). Despite advances in medicine and health GDM is still prevalent among pregnant women, resulting in possible complications to pregnancy such as, fetal distress, preterm delivery, low birth weight, as well as risk of type 2 diabetes to the mother (1). Research links vitamin D receptor (VDR), which is also found in islet beta cells, to insulin secretion, thus possibly helping manage GDM (1). A recent study was conducted to further evaluate various doses of vitamin D and†¦show more content†¦The sample size was a bit small considering the general population of GDM, a more comprehensive population would range into the thousands, but this sample size was a good starting point for further research. Group one w as the control group and received the placebo, group two received a low dose of 200 IU of Vitamin D daily, group three received a medium dose of 50,000 IU of vitamin D within a month, and group four received a total of 10,000 IU within a month (1). Administration of vitamin D supplementation occurred between 24-28 weeks of pregnancy and continued until delivery, and a follow up examination occurred once a month (1). The research team also measured the participants’ dietary intake to ensure they had similar diets to ensure diets did not interfere with the results (1). Fasting plasma glucose, serum insulin, insulin resistance, total cholesterol change, and triglyceride levels were all measured with commercial ELISA kits (1). The oral glucose tolerance test is used as the gold standard for measuring the efficiency in glucose metabolism (4). This current study chose to do A1c ELISA kits for efficiency as the oral glucose tolerance test takes several hours to complete (1). 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